Browsing Tag

Chromatin

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Multimodal chromatin profiling using nanobody-based single-cell CUT&Tag thumbnail

Multimodal chromatin profiling using nanobody-based single-cell CUT&Tag

MainCell identity and the underlying gene expression programs are determined through the action of epigenetic modalities including transcription factor binding1, modifications of histones2, chromatin remodeling3, DNA methylation4, genome architecture5 and long non-coding RNAs6. Together, effects of these factors determine the regulatory logic behind cell state transitions during development and in disease. Changes in the chromatin
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Paleontologists Find Chromatin Threads in Fossilized Dinosaur Cartilage thumbnail

Paleontologists Find Chromatin Threads in Fossilized Dinosaur Cartilage

Paleontologists have analyzed cartilage material from Caudipteryx, an oviraptorosaurid dinosaur that lived in what in now China some 125 million years ago (Early Cretaceous epoch) and was part of the famous Jehol Biota. Photograph and line drawing of the Caudipteryx specimen. Image credit: Zheng et al., doi: 10.1038/s42003-021-02627-8. “Geological data has accumulated over the years…
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