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Opioid-Induced

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Buprenorphine May Curb Opioid-Induced Respiratory Depression thumbnail

Buprenorphine May Curb Opioid-Induced Respiratory Depression

High plasma concentrations of buprenorphine may reduce fentanyl-induced respiratory depression, new research suggests. The primary endpoint measure in a small "proof of principal" pharmacology study was effect of escalating fentanyl dosing on respiratory depression by way of decreased isohypercapnic minute ventilation (VE) ― or volume of gas inhaled or exhaled per minute from the lungs.…
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