A skin patch with microneedles that inject mRNA reduced wrinkles in mice with UV-damaged skin, a technique that could be used to treat skin conditions and arthritis related to collagen deficiency
By Grace Wade
A microneedle patch could reduce wrinkles
Shutterstock/DUANGJAN J
Using mRNA to direct the body to make more collagen – the most abundant protein in skin – reduces wrinkles in mice. This therapy could be useful to treat other disorders related to collagen loss, including some genetic skin conditions and arthritis.
Wrinkles form, in part, because UV radiation from the sun damages collagen fibres in skincausing it to lose structure and elasticity. Medical treatments that use mRNA, such as covid-19 vaccinesprovide cells in the body with genetic instructions for producing proteins. To …
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