The digits are different from Japan …!
I’m buried in the news of Corona every day, but the medical world continues to break through. In the United States, the number of organ transplants carried out in the last year reached the 40,000 mark one week before Christmas, surpassing the 39,700 cases in 2019. Reached the highest. In the end, it is expected to be around 415,000 cases a year, and it is calculated that 114 people’s lives were saved a day.
Algorithm matches donor and patient
Judges this many numbers Is not easy. Even in the United States, a developed country for transplantation, transplantation has been repeated in almost the same hospital for 30 years since the first successful liver transplantation in 1954. If no patient waiting for a transplant was found in the neighborhood, the organ was poi.
The turning point came in 1984. It was decided by the Diet to expand to a nationwide scale and leave matching to private NPOs, and UNOS (United Network for Organ Sharing) was announced by 57 OPOs (Organ Procurement Organizations) and hospitals in the United States. A style that collects data and promotes recipient selection (matching of adaptation conditions such as blood type, antibody reaction, and size) using the algorithm. The scale has expanded. From 2004 to 2012, the number was flat at around 28,000, but from 2013 it has increased by nearly 50%. In 2020, there was a period when transplantation was not possible for 8 weeks, so it started to decrease, but it has recovered.
Matching that UNOS’s local media Richmond Times–Dispatch is worrisome I am interviewing in detail about the flow of the above, but it seems that the algorithm is constantly improving, and at the time of revision, the board of directors consisting of 44 people has approved it through trial. The algorithm considers how long the transplant can prolong the life and whether the body can withstand the transplant. Celebrities, rich people, and people with good insurance will not be given priority.
We are also tracking the following data.
・ Number of patients waiting for organs
・ Number of patients dying before the arrival of organs (by hospital)
・ Hospitals that prefer young and healthy organs ・ Doctors
・ After the rejected organs (whether they were used for transplantation at other hospitals)
・ Patient’s remaining life without organ transplantation
Doctor picks up organs We are also preparing a mechanism to check the condition of organs in advance with photos and videos so that you do not have to go and inspect directly. Various things are amazing.
The majority of the people are donors
When you get a driver’s license in the United States If you select the item “Donate after death”, it will be displayed on your driver’s license so that you can see the person in the ambulance at a glance. Perhaps because of such ease, according to UNOS CEO Brian Shepard, there are about 50% of Americans who have registered for body donation. What the majority of the people were donors! No, the translator is also a permanent resident, but I chose YES for the donation.
By the way, in the United States, 50,000 people died from opioid analgesic addiction in 2019 alone, but deaths from drug overdose (in 2020 93,331 people ) are 1% of the increase in donations. Since the dead from COVID-19 cannot donate, it seems that the number of healthy donors who want to help people has increased in the midst of such a deep turmoil.
In the fall, I transplanted a pig kidney to a brain-dead patient for the first time, and I was able to urinate well!
Well, even with the understanding and cooperation of the people and the efforts of related organizations, about 110 people are waiting for a transplant a day, and 30 of them are organs. The reality is that I can’t wait for my death and my condition is getting worse. Overwhelming lack of organs.
Doctors noticed to do something about this Pig organs
and. In September of last year, the New York University Langon Transplant Institute succeeded in the first transplant operation, and the second operation in late November was also successful, which was a great hope.
The following two recipients are interested.
・ September: Brain-dead patient just before removing the life support system. The family agreed, “If it’s good for research.”
・ November: Donor applicants who cannot maintain their physical function when the ventilator is removed. I found it with the cooperation of LiveOnNY, a non-profit organization that has 6.5 million registered donors in NY.
The kidney is connected to the blood vessels of the upper thigh instead of the original part and covered with a protective material for 54 hours. I observed the progress, but there was no rejection on both occasions, and I immediately got the same amount of urine as a human organ transplant . . Dr. Robert Montgomery, who led the surgery, said in a statement that he was delighted.
“I was able to reproduce the results of the first surgery for the second time. It continues to be shown that genetically engineered organs (to prevent rejection) can be a source of regenerative organs for people around the world who are waiting for the gift of life. ”
Unlike other mammals, human organs are α-gal. ) Cannot produce sugar. Therefore, if an organ that can be produced is transplanted to an organ that cannot be produced, a rejection reaction will inevitably occur. Was handled by Revivicor, a subsidiary of United Therapeutics). That’s why you don’t have to worry about causing allergies.
If you think that some people may feel resistance to animal organs, surprisingly According to the opinion poll , the majority of people answered, “If it spreads, I will support it.” The practical application of xenotransplantation is still a long way off, but if the number of people who die while waiting for organs is reduced, there is no news that encourages us so much!
Sources: Richmond Times–Dispatch , NYU Langone Health , Gizmodo US
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