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cluster

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Eye drop product may be tied to cluster of drug-resistant bacterial infections, CDC says thumbnail

Eye drop product may be tied to cluster of drug-resistant bacterial infections, CDC says

Home News Federal health officials are investigating a cluster of drug-resistant bacterial infections. (Image credit: KATERYNA KON/SCIENCE PHOTO LIBRARY via Getty Images) The U.S. Centers for Disease Control and Prevention (CDC) has advised doctors and consumers to "immediately discontinue" the use of EzriCare Artificial Tears, as the eye drops may be linked to a multistate
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CLUSTER guide RNAs enable precise and efficient RNA editing with endogenous ADAR enzymes in vivo thumbnail

CLUSTER guide RNAs enable precise and efficient RNA editing with endogenous ADAR enzymes in vivo

AbstractRNA base editing represents a promising alternative to genome editing. Recent approaches harness the endogenous RNA-editing enzyme adenosine deaminase acting on RNA (ADAR) to circumvent problems caused by ectopic expression of engineered editing enzymes, but suffer from sequence restriction, lack of efficiency and bystander editing. Here we present in silico-optimized CLUSTER guide RNAs that bind…
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