Browsing Tag
High-throughput
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High-throughput screening of TnpB proteins identifies hypercompact genome editors
Research Briefing Published: 29 June 2023 Nature Biotechnology (2023)Cite this article 904 Accesses 2 Altmetric Metrics details Subjects TnpB proteins are hypercompact RNA-guided DNA endonucleases. By systematically mining and characterizing TnpB proteins from the IS605 family, we identified potent genome editors and established a framework for high-throughput annotation and screening of TnpB systems in prokaryotic