Browsing Tag
single-nucleotide
2 posts
Single-nucleotide variant calling in single-cell sequencing data with Monopogen
MainDefining the precise cellular contexts in which risk-associated variants affect cellular processes will help to better understand the molecular mechanisms of disease risks and to inform therapeutic strategies. This is important because recent studies have shown that many genetic variants affect tissue traits in a cell-type-specific manner1,2. Traditional bulk RNA analysis is usually biased toward
A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation | Science
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