The pathology of the placenta in pregnancies in which Corona virus ( SARS-CoV-2 ) has been observed Seemingly non-specific. However, the identification of placental lesions caused by corona infection will be a significant step forward, which will make it possible to improve the management of pregnancies and identify the mechanisms involved in a possible vertical transfer.
In a study published in the journal Modern Pathology , the researchers examined the pathological findings in the placentas of 198 pregnant women who were positive for corona to identify lesions associated with the virus. .
For the purpose of detecting corona infection, the researchers used immunohistochemistry, and positive cases were further confirmed using tests ISH . In 33 cases, corona virus infection was also investigated using RT-PCR , including all cases found to be positive by immunohistochemical testing. In nine cases, positive results were obtained for corona in immunohistochemical examination, ISH and
RT-PCR .
In these placentas were found lesions characterized by basic necrosis ( villi ) The trophoblast, collapses in the space between the stems, and varying levels of inflammatory filtrate mixed between the stems, and fibrinoid deposits around the stems.
The range of these lesions ranges from a targeted lesion, to a massive spread of the lesions in five cases, leading to intrauterine fetal death.
Evidence of infection in Corona was observed among two of the dead fetuses. In 189 the remaining placentas were not found to have similar lesions.
The strong association between trophoblastic injury and placental infection with the coronavirus indicates that this lesion is a specific marker of coronary heart disease. Extensive trophoblastic damage, which massively affects placental sissy tissue, can result in fetal death associated with corona disease ( COVID-19 ).
Source:
Garrido-Pontnou, M et al . Modern Pathology. 2021 Sep; 34 (9): 1704-1709.doi: 10.1038 / s41379-021-00827-5
Note: This article has been indexed to our site. We do not claim legitimacy, ownership or copyright of any of the content above. To see the article at original source Click Here
FORTNITE Digital V-Bucks 5000 - PlayStation/Xbox/Nintendo Switch/PC/Mobile [Digital Code]
$36.99 (as of November 20, 2024 18:57 GMT +00:00 - More infoProduct prices and availability are accurate as of the date/time indicated and are subject to change. Any price and availability information displayed on [relevant Amazon Site(s), as applicable] at the time of purchase will apply to the purchase of this product.)
MontNorth Collapsible Basin Bucket,9L Collapsible Dishpan with Drain Plug for Kitchen Sink,5L Portable Foldable Small Plastic Water Supplies for Outdoor Garden Camping Fishing Car Wash(Sets of 2)
$16.99 (as of November 20, 2024 18:57 GMT +00:00 - More infoProduct prices and availability are accurate as of the date/time indicated and are subject to change. Any price and availability information displayed on [relevant Amazon Site(s), as applicable] at the time of purchase will apply to the purchase of this product.)
Apple AirTag
$19.99 (as of November 20, 2024 19:20 GMT +00:00 - More infoProduct prices and availability are accurate as of the date/time indicated and are subject to change. Any price and availability information displayed on [relevant Amazon Site(s), as applicable] at the time of purchase will apply to the purchase of this product.)
HP Probook X360 11 G2 2-in-1 11.6 Inch Touchscreen Laptop, Intel Core i5-8200Y, 8GB RAM, 256GB SSD, Windows 10 Pro (Renewed)
$104.99 (as of November 19, 2024 18:55 GMT +00:00 - More infoProduct prices and availability are accurate as of the date/time indicated and are subject to change. Any price and availability information displayed on [relevant Amazon Site(s), as applicable] at the time of purchase will apply to the purchase of this product.)
